Friday, April 27, 2012

Its all about your blood sugar

The ONE Number That May Best Predict Your Risk of Sudden Death
Posted by: Dr. Mercola | April 27 2012



Story at-a-glance
There are seven numbers you should track if you want to monitor your health—five are determined by simple blood tests, and the other two you can determine at home
The five blood tests you should regularly obtain are fasting insulin, cholesterol/HDL ratio, serum ferritin, uric acid, and vitamin D; two good indicators for assessing your overall “metabolic fitness” and heart attack risk are your percentage body fat and your waist-to-hip ratio
Optimizing your vitamin D level is crucial for health because vitamin D influences about 3,000 of your 30,000 genes, helping to prevent a multitude of diseases from cardiovascular disease to the common cold
Minimizing dietary sugar, especially fructose, will go a long way toward optimizing nearly ALL seven of these numbers—if you could do only one thing, this would be the one!
By Dr. Mercola

The Globe and Maili recently published an article outlining "the 5 numbers that most impact your health."

I think they have the right idea, but but I disagree with their test selections.

If you really want to monitor your health, I believe the numbers you should be tracking are the seven listed in the table below.

These are far more important than tracking your total cholesterol, blood pressure, or BMI, as recommended by the Globe and Mail.

Let's take a closer look at these values and what they may reveal about your health.


1. Fasting Insulin (I)
2. Cholesterol/HDL Ratio (C)
3. Percentage Body Fat (F)
4. Serum Ferritin (F)
5. Waist/Hip Ratio (WH)
6. Uric Acid Level (U)
7. Vitamin D Level (D)
1. Fasting Insulin Level



Your fasting insulin level reflects how healthy your blood glucose levels are over time. Insulin helps sugar move from your blood into your cells, where it can be used or stored. Chronically elevated blood glucose leads to insulin resistance and numerous chronic diseases, including diabetes and heart disease. Elevated blood glucose and insulin resistance are epidemic today. An estimated one in four Americans are either insulin resistant or diabetic.

One of the most frequent causes of elevated glucose (and insulin resistance) is consumption of too many grains and sugars. Fructose has been shown to be especially harmful due to the way it disrupts the lock-and-key fit between insulin and its cellular receptor sites. Fructose is a powerful endocrine disruptor, capable of rapidly inducing insulin resistance when consumed in what, by today's standards, is a relatively small amount (25 grams or more per day).

Your fasting insulin level can be determined by a simple, inexpensive blood test. A normal fasting blood insulin level is below 5, but ideally you'll want it below 3. If your insulin level is higher than 3 to 5, the most effective way to optimize it is to reduce or eliminate all forms of dietary sugar, particularly fructose.

You can also use a simple glucose test to check your fasting glucose level. Just realize that it's possible to have low fasting glucose but still have significantly elevated insulin levels.Generally speaking, a fasting glucose under 100 mg/dl suggests you're not insulin resistant, while a level between 100 and 125 suggests you're either mildly insulin resistant or have impaired glucose tolerance (sometimes referred to as pre-diabetes).

2. Cholesterol/HDL Ratio



Cholesterol has been demonized for the past few decades, thanks to a landmark study by Dr. Ancel Keys in 1953 that has been used to justify a low fat diet approach to achieve health. This study resulted in cholesterol's being blamed for just about every case of heart disease in the last 20 years. But the fact is, cholesterol is most likely not going to destroy your health (as you have been led to believe), and is also not the cause of heart disease. Most of the recent credible science has debunked Keys' theory, but the cholesterol myth stubbornly persists in the mainstream because it's so deeply embedded in our culture.

We now know that your body actually requires cholesterol to manufacture vitamin D from sunlight, to synthesize sex hormones, and for proper brain function. Measuring total blood cholesterol tells you practically nothing about your heart disease risk. More value can be derived by looking at the relative types of lipids circulating in your bloodstream, and today we have sophisticated tests that can measure these. The following two ratios are far better indicators of heart disease risk than total cholesterol alone:

Your HDL/Cholesterol ratio: HDL (high-density lipoproteins) to total cholesterol percentage is a very good predictor of heart disease risk. Just divide your HDL number by your total cholesterol. Ideally, this number should exceed 24 percent; below 10 percent predicts an increased risk for heart disease.
Your Triglyceride/HDL ratio: Divide your triglyceride number by your HDL. This percentage should ideally be below 2.
3. Percentage Body Fat

Body composition, meaning your relative amounts of lean body mass to body fat, is a powerful way to measure your overall health. There is a strong correlation between higher body fat and negative health outcomes, such as heart disease and stroke. And percentage of body fat says more about your overall fitness than body weight or body mass index (BMI). BMI can be particularly misleading, causing fit bodybuilders to be classified as overweight as it does not take into account the higher weight of muscle compared to fat. Also, increased organ or abdominal adipose tissue in particular (a "beer belly") has been shown to be more strongly associated with heart disease and a variety of chronic diseases than just weight in relation to height.

The most common way to assess body fat percentage is the skinfold measurement technique, which utilizes a skinfold caliper. (Skinfold measurement is the method most widely used by fitness trainers.) The American Council on Exercise provides the following percentage body fat guidelinesii for men and women:

Category Women Men
Essential Fat 10-13% 2-5%
Athletes 14-20% 6-13%
Fitness 21-24% 4-17%
Acceptable 25-31% 18-24%
Obesity >32% >25%


For even greater accuracy, you can resort to hydrostatic weighing, where you get weighed under water. This measures the density of your body, which is then used to calculate how much body fat you have.

Another technique that is gaining support by medical and fitness experts is the bioelectrical impedance analysis (BIA). To measure body impedance, an electrical signal is passed through your body. Impedance is greatest in fat tissue, which contains low amounts of water, while fat-free mass, which contains up to 75 percent water, allows the signal to pass through fairly unimpeded. This measurement, along with other factors such as your height, weight, and body type, is then used to calculate your percentage of body fat, fat-free mass and other body composition values.

There are now bathroom scales that use this technology. I picked one up from Eat Smartiii that I have been using for the last four months. I find it's a simple way to monitor my body fat percentage. It may overestimate a bit as it has me at 13.5 percent when I tested between 11 and 12 percent using other methods, but it is very accurate in measuring day to day variability, and can be an excellent and inexpensive way to monitor your progress on optimizing your body fat so it is line with your health goals.

4. Serum Ferritin



You probably already know that iron is an important nutrient for your body. But you might not be aware that iron is a double-edged sword—both too much and too little can lead to major health problems.

Iron serves many functions in your body, but one of the most important is carrying oxygen throughout your body by binding to hemoglobin molecules in your bloodstream. Without proper oxygenation, your cells quickly begin to die. If you don't have enough iron in your body, you end up with iron deficiency anemia, a common problem among children and menstruating women. But your body also has a limited capacity to excrete iron, so it can build up in your tissues if you're getting too much in your diet.

Processed foods fortified with iron and multivitamins with iron can contribute to iron overload over time. The problem with excess iron is that it's also a very potent oxidative stressor, causing dangerous free radicals that can damage your heart and your DNA, and lead to diseases such as cancer. Therefore, you should regularly check yourself for iron overload with a serum ferritin test. This blood test measures iron's carrier molecule—a protein called ferritin found inside your cells upon which the iron is stored. If your ferritin levels are low, it means your iron levels are also low, and vice versa. Use the following guidelines to interpret your serum ferritin level:

The healthy range of serum ferritin is between 20 and 80 ng/ml
The ideal serum ferritin range is 40 to 60 ng/ml
Below 20, you are iron deficient; above 80, you have an iron surplus.Ferritin levels can go really high. I've seen levels over 1,000, but anything over 80 is likely to be a problem.
It is VITAL to appreciate that about one in five men and postmenopausal women have iron levels that are too high and are actually causing premature disease and death. If you or someone you love has triple digit ferritin levels you need to lower them ASAP. The higher the number the worse it is, with numbers over 250-300 being particularly dangerous. Fortunately there is a very simple way to lower it. I would not advise using supplements like phytic acid (IP6), which can bind other helpful minerals. The single best way to lower your iron is to simply donate blood. If you have risk factors that prevent you from having your blood accepted for donation, you can have your doctor write you a prescription for a therapeutic phlebotomy.

5. Waist Size

There is scientific evidenceiv that BMI (body mass index) is a very flawed measurement when it comes to predicting your risk of dying from heart disease. Waist size provides a far more accurate benchmark for predicting your risk of death from a heart attack and from other causes. Determining your waist size is easy. With a tape measure, measure the distance around the smallest area of your abdomen, below your rib cage and above your belly button. The following is a general guide for healthy waist circumference:

Men: 37 to 40 inches is overweight; greater than 40 inches is obese
Women: 31.5 to 34.6 inches is overweight; greater than 34.6 inches is obese
The reason why this is a better indicator of heart disease risk is because your waist size is related to the type of fat that is stored around your waistline, called "visceral fat" or "belly fat." This type of fat is strongly linked to type 2 diabetes, heart disease, stroke, and other chronic diseases. It is thought that visceral fat is related to the release of proteins and hormones that cause inflammation, which can in turn damage your arteries and affect how you metabolize sugars and fats. An expanded waistline is associated with insulin resistance, high blood pressure, lipid imbalance, cardiovascular disease, thickening of the walls of your heart, and even increased risk for developing Alzheimer's disease decades later.

6. Uric Acid Level

You may already know that elevated uric acid levels cause gout. But did you know uric acid can serve as a marker for fructose toxicity?

Fructose, when over-consumed, is very taxing to your body's metabolic processes. One of the by-products of fructose metabolism is uric acid, so when you consume too much sugar—particularly concentrated fructose—your uric acid levels may rise. Fructose turns you into a uric acid factory! Elevated uric acid is thought to explain much of the damage fructose causes in your body. This is especially pronounced if you are particularly fructose-sensitive, as I am. I'm grateful to Dr. Richard Johnson, author of The Sugar Fix, for bringing the uric acid link to my attention. As an aside I have helped proof his new book, The Fat Switch, which is beyond phenomenal and will also be available shortly.

The connection between fructose consumption and increased uric acid is so reliable that a uric acid level taken from your blood can actually be used as a marker for fructose toxicity. I now recommend that a uric acid level be a routine part of your blood screening.

According to the latest research, the safest range for uric acid is between 3 and 5.5 milligrams per deciliter, and there appears to be a steady relationship between uric acid levels and blood pressure and cardiovascular risk, even down to the range of 3 to 4 mg/dl. As you know, two-thirds of the U.S. population is overweight, and most of these people likely have uric acid levels in excess of 5.5. Some may even be closer to 10 or higher. Dr. Johnson suggests that the ideal uric acid level is probably around:

4 mg/dl for men, and
3.5 mg/dl for women
7. Vitamin D Level



Vitamin D deficiency is at epidemic levels in the United States, but many Americans—including many physicians—are still unaware of the implications. In the U.S., the late winter average vitamin D is only about 15 to 18 ng/ml, which is considered a very serious deficiency state. In fact, 85 percent of Americans may be deficient in vitamin D, including more than 95 percent of all seniors.

Vitamin D influences about 3,000 of the 30,000 genes in your body, which is why it's involved with the expression of so many diseases, from cancer to autism to heart disease and rheumatoid arthritis, just to name a few. A study by vitamin D expert Dr. William Grant, Ph.D., found that about 30 percent of cancer deaths could be prevented each year with higher levels of vitamin D. Beyond preventing cancer, researchers have estimated that increasing vitamin D levels could prevent diseases that claim nearly one million lives globally each year. Vitamin D also fights colds and flu because it helps your immune system defend against bacteria and viruses.

You should regularly check your vitamin D level, but you must obtain the correct test. There are two vitamin D tests: 1,25(OH)D and 25(OH)D. Of the two, 25(OH)D (also called 25-hydroxyvitamin D) is the better marker of overall vitamin D status.

The following ranges were obtained in a large-scale clinical study by evaluating healthy people in tropical or subtropical parts of the world, where they are receiving healthy sun exposures. It seems more than reasonable to assume that these values are in fact reflective of an optimal human requirement. When getting your vitamin D level tested, please realize that many commercial labs are using old, outdated reference ranges, and that their "normal" is likely to be far below these optimal and clinically relevant values.



(Holick MF. Calcium and Vitamin D. Diagnostics and Therapeutics. Clin Lab Med. 2000 Sep;20(3):569-90)

If your vitamin D level is too low, the best way to increase it is with exposure to natural sunlight, in appropriate amounts, or using a safe tanning bed. If neither of those options are feasible, you can opt for an oral vitamin D3 supplement. Just remember that if you supplement orally, it is even MORE important to have your blood levels checked regularly, as there is a wide variation in how efficiently people absorb vitamin D orally.

While the latest research indicates adults need about 8,000 IU's of vitamin D per day to achieve vitamin D levels of 40 ng/ml, you need to monitor your levels carefully in order to determine the dosage you need in order to reach and maintain optimal levels, as this is highly variable. There is no magic dosage when it comes to vitamin D; rather it's the serum level that really matters.

For more information about vitamin D testing, refer to my comprehensive article on the topic. I also strongly recommend you watch my one-hour vitamin D lecture, included at the top of this section.

References:

i Globe and Mail January 5, 2012
ii American Council on Exercise
iii Amazon.com, EatSmart Precision GetFit Digital Body Fat Scale w/ 400 lb. Capacity & Auto Recognition Technology
iv J Am CollCardiol May 10, 2011

Source: The Globe and Mail January 5, 2012
Related Links:

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Friday, April 13, 2012

The myth of bad genes, bad bugs, bad luck

Falling for This Myth Could Give You Cancer
Posted By Dr. Mercola | April 11 2012

Story at-a-glance
Science has shattered the Central Dogma of molecular biology, proving that determinism—the belief that your genes control your health—is false. You actually have a tremendous amount of control over how your genetic traits are expressed, by changing your thoughts and altering your diet and your environment
In 1988, the experiments of John Cairns demonstrated even primitive organisms can evolve “consciously,” as DNA changes in response to its environment. The cell’s “consciousness” lies in its membrane, which contains receptors that pick up various environmental signals. This mechanism controls the “reading” of the genes inside the cell
The work of Dr. Bruce Lipton and other epigenetic researchers shows that the “environmental signals” also include thoughts and emotions—both of which have been shown to directly affect DNA expression
Contrary to the Newtonian belief in your body as a biological machine, epigenetic science reveals that you are an extension of your environment, which includes everything from your thoughts and belief systems, to toxic exposures and exposure to sunlight, exercise, and, of course, everything you choose to put onto and into your body. Epigenetics shatters the idea that you are a victim of your genes, and shows that you have tremendous power to shape and direct your physical health
By Dr. Mercola

How much control do you really have over your own life in general, and your health in particular?

These questions have puzzled many since the beginning of time.

Now, the emerging science of epigenetics is offering some answers that put true control within your reach.

According to some scientists, changing your health may be as "simple" as changing your thoughts and beliefs.

"Contrary to what many people are being led to believe, a lot of emphasis placed on genes determining human behavior is nothing but theory and doctrine," writes Konstantin Erikseni .

"We are free to make decisions that impact our lives and those of others. …

Our beliefs can change our biology.

We have the power to heal ourselves, increase our feelings of self-worth and improve our emotional state."

Epigenetics Shatters "The Central Dogma"

Eriksen goes on to discuss something called "The Central Dogma" of molecular biology, which states that biological information is transferred sequentially and only in one direction (from DNA to RNA to proteins).

The ramification of buying into the central dogma is that it leads to belief in absolute determinism, which leaves you utterly powerless to do anything about the health of your body; it's all driven by your genetic code, which you were born with.

However, scientists have completely shattered this dogma and proven it false. You actually have a tremendous amount of control over how your genetic traits are expressed—from how you think to what you eat and the environment you live in.

You may recall the Human Genome Projectii , which was launched in 1990 and completed in 2003. The mission was to map out all human genes and their interactions, which would than serve as the basis for curing virtually any disease. Alas, not only did they realize the human body consists of far fewer genes than previously believed, they also discovered that these genes do not operate as previously predicted.

In the featured article, Eriksen describes the experiments of John Cairns, a British molecular biologist who in 1988 produced compelling evidence that our responses to our environment determine the expression of our genes. A radical thought, for sure, but one that has been proven correct on multiple occasions since then.

Eriksen writesiii :

"Cairns took bacteria whose genes did not allow them to produce lactase, the enzyme needed to digest milk sugar, and placed them in petri dishes where the only food present was lactase. Much to his astonishment, within a few days, all of the petri dishes had been colonized by the bacteria and they were eating lactose. The bacterial DNA had changed in response to its environment. This experiment has been replicated many times and they have not found a better explanation than this obvious fact – that even primitive organisms can evolve consciously.

So, information flows in both directions, from DNA to proteins and from proteins to DNA, contradicting the "central dogma." Genes can be activated and de-activated by signals from the environment. The consciousness of the cell is inside the cell's membrane. Each and every cell in our bodies has a type of consciousness. Genes change their expression depending on what is happening outside our cells and even outside our bodies."

Your Emotions Regulate Your Genetic Expression

As if genes changing expression in response to environmental factors such as nutrients wasn't enough, other researchers have demonstrated that this "environment" that your genes respond to also includes your conscious thoughts, emotions, and unconscious beliefs. Cellular biologist Bruce Lipton, PhD., is one of the leading authorities on how emotions can regulate genetic expression, which are explained in-depth in his excellent books The Biology of Belief, and Spontaneous Evolution.

Science has indeed taken us far beyond Newtonian physics, which says you live in a mechanical universe. According to this belief, your body is just a biological machine, so by modifying the parts of the machine, you can modify your health. Also, as a biological machine, your body is thought to respond to physical "things" like the active chemicals in drugs, and by adjusting the drugs that modify your machinery, doctors can modify and control health. However, with the advent of quantum physics, scientists have realized the flaws in Newtonian physics, as quantum physics shows us that the invisible, immaterial realm is actually far more important than the material realm. In fact, your thoughts may shape your environment far more than physical matter!

According to Dr. Lipton, the true secret to life does not lie within your DNA, but rather within the mechanisms of your cell membrane.

Each cell membrane has receptors that pick up various environmental signals, and this mechanism controls the "reading" of the genes inside your cells. Your cells can choose to read or not read the genetic blueprint depending on the signals being received from the environment. So having a "cancer program" in your DNA does not automatically mean you're destined to get cancer. Far from it. This genetic information does not ever have to be expressed...

What this all means is that you are not controlled by your genetic makeup. Instead, your genetic readout (which genes are turned "on" and which are turned "off") is primarily determined by your thoughts, attitudes, and perceptions!

The major problem with believing the myth that your genes control your life is that you become a victim of your heredity. Since you can't change your genes, it essentially means that your life is predetermined, and therefore you have very little control over your health. With any luck, modern medicine will find the gene responsible and be able to alter it, or devise some other form of drug to modify your body's chemistry, but aside from that, you're out of luck… The new science, however, reveals that your perceptions control your biology, and this places you in the driver's seat, because if you can change your perceptions, you can shape and direct your own genetic readout.

This new science also reveals that you are in fact an extension of your environment, which includes everything from your thoughts and belief systems, to toxic exposures and exposure to sunlight, exercise, and, of course, everything you choose to put onto and into your body. As Dr. Lipton is fond of saying, the new biology moves you out of victimhood and into Mastery—mastery over your own health.

It is a supreme confirmation of my favorite saying, "You Can Take Control of Your Health."

How Nutrition Alters Genetic Expression

Two years ago, a study performed by the Linus Pauling Institute at Oregon State University was showcased at the annual Experimental Biology convention. The study demonstrated how "histone modifications" can impact the expression of many degenerative diseases, ranging from cancer and heart disease to biopolar disorder and even aging itself. According to Rod Dashwood, a professor of environmental and molecular toxicology and head of LPI's Cancer Chemoprotection Program, as quoted in a press releaseiv:

"We believe that many diseases that have aberrant gene expression at their root can be linked to how DNA is packaged, and the actions of enzymes such as histone deacetylases, or HDACs. As recently as 10 years ago we knew almost nothing about HDAC dysregulation in cancer or other diseases, but it's now one of the most promising areas of health-related research."

In a nutshell, we all have tumor suppressor genes, and these genes are capable of stopping cancer cells in their tracks. These genes are present in every cell in your body, but so are proteins called "histones." As Dr. Jean-Pierre Issa at the M.D. Anderson Cancer Center explainsv , histones can "hug" DNA so tightly that it becomes "hidden from view for the cell." If a tumor suppressor gene is hidden, it cannot be utilized, and in this way too much histone will "turn off" these cancer suppressors, and allow cancer cells to proliferate.

Now here's where epigenetics comes in … certain foods, such as broccoli and other cruciferous vegetables, garlic, and onions contain substances that act as histone inhibitors, which essentially block the histone, allowing your tumor suppressor genes to activate and fight cancer. By regularly consuming these foods, you are naturally supporting your body's ability to fight tumors.

Certain alternative oncologists also tap directly into the epigenetic mechanism, such as Dr. Nicholas Gonzalez, who uses a three-pronged approach to cancer based primarily on nutrition and detoxification, and Dr. Stanislaw Burzynski, who treats cancer with a gene-targeted approach. His treatment uses non-toxic peptides and amino acids, known as antineoplastons, which act as genetic switches that turn your tumor suppressor genes "on."

A Healthy Lifestyle Supports Healthy Genetic Expression

So the good news is that you are in control of your genes … You can alter them on a regular basis, depending on the foods you eat, the air you breathe, and the thoughts you think. It's your environment and lifestyle that dictates your tendency to express disease, and this new realization is set to make major waves in the future of disease prevention -- including one day educating people on how to fight disease at the epigenetic level. When a disease occurs, the solution, according to epigenetic therapy, is simply to "remind" your affected cells (change its environmental instructions) of its healthy function, so they can go back to being normal cells instead of diseased cells.

You can begin to do this on your own, long before you manifest a disease. By leading a healthy lifestyle, with high quality nutrition, exercise, limited exposure to toxins, and a positive mental attitude, you encourage your genes to express positive, disease-fighting behaviors.

This is what preventive medicine is all about. It's not about taking any one particular nutrient as a supplement to fix one specific "part" of your biological machinery... The more people become willing to embrace this simple truth, the healthier everyone will get.

It's also worth pointing out that epigenetic effects begin before birth.

Epigenetic research from 2009 showed that rat fetuses receiving poor nutrition in the womb become genetically primed for a nutrition-poor environment. As a result of this genetic adaptation, the rats tended to be smaller. They were also at higher risk for a host of health problems throughout their lives, such as diabetes, growth retardation, cardiovascular disease, obesity, and neurodevelopmental delays. Again, while some are tempted to blame such "predispositions" on bad genes, the KEY factor is nutrition, i.e. the cellular environment.

If you're ready to address your dietary choices, read through my comprehensive nutrition plan, which will give you tips and tools for eating healthy, dealing with stress, and living a lifestyle that will support your epigenetic health.

You can also turn your genes off and on with your emotions too. Many, if not most people carry emotional scars; traumas that can adversely affect health. Using techniques like energy psychology, you can go in and correct the trauma and help regulate your genetic expression. My favorite technique for this is the Emotional Freedom Technique (EFT), but there are many others. Choose whichever one appeals to you, and if you don't sense any benefits, try another, until you find what works best for you.

Please, remember that 'You CAN Take Control of Your Health.'

References:

i Wake Up World March 26, 2012
ii The Human Genome Project
iii Wake Up World March 26, 2012
iv 'Epigenetic' concepts offer new approach to degenerative disease, Eurekalert April 28, 2010
v Epigenetic Therapy, NOVA, October 16, 2007
Source: Wake Up World March 26, 2012

Monday, April 9, 2012

Sleep, perchance to dream

This Common Sleeping Mistake Can Double Your Risk of a Heart Attack
Posted By Dr. Mercola | April 09 2012 |

Story at-a-glance
Research indicates that sleeping less than six hours may increase insulin resistance and diabetes. It may also double risk of angina, coronary heart disease, heart attack or stroke. The same appears to be true when you sleep more than nine hours per night.
Humans are biologically programmed to nap during the daytime. Training your body to resist the urge to nap in the afternoon can lead to inability to easily fall asleep at night.
Ideally, you should sleep enough hours so that your energy is sustained through the day without artificial stimulation, with the exception of a daytime nap.
Engaging in shift work dramatically increases mortality. Preliminary data shows that increasing melatonin levels during your night shift—effectively turning it into an artificial day—you can minimize some of the detrimental effects.
By Dr. Mercola

In my experience, you can have the best diet in the world, have the best exercise program and be free from emotional stress, but if you aren't sleeping well, for whatever reason, it is virtually impossible to be healthy.

But how much sleep do you need for optimal health?

In this interview, Dr. Rubin Naimani -- a clinical psychologist, author, teacher, and the leader in integrative medicine approaches to sleep and dreams—sheds light on this question.

Dr. Naiman earned his Ph.D. in Clinical Psychology at Alliant University in San Diego.

During the 1990's, he served as the sleep and dream specialist at Canyon Ranch Health Resort in Tucson for 10 years, where he created the first formal sleep laboratory outside of a hospital setting.

Dr. Andrew Weil was also on the staff at that time. Later, he served as director of sleep programs for Miraval Resort. In previous interview, we discussed what sleep actually is, the spiritual dimensions of sleep, the primary causes of insomnia, and why sleeping pills are not the answer. Here, Dr. Naiman delves into several of the most frequently asked questions about sleep, starting with:

How Much Sleep Do You Need?

Over the years, I've come to a conclusion that there is no perfect answer to this question because like everything else, the answer depends on a large number of highly individual factors. The general consensus seems to be that most people need somewhere between six and eight hours of sleep each night.

There's compelling research indicating that sleeping less than six hours may increase your insulin resistance and risk of diabetes. And recent studies show that less than five hours of sleep at night can double your risk of being diagnosed with angina, coronary heart disease, heart attack or stroke. Interestingly enough, the same appears to be true when you sleep more than nine hours per night.

The question of the ideal amount of sleep is a topic Dr. Naiman has addressed on numerous occasions throughout his career as a sleep expert, and he agrees; people want a number, but this 'number' must be as individual as the person asking for it.

"I think asking 'how many of hours of sleep should I get?' is like asking, 'Doctor, how many calories should I eat?'" he says. "Of course the answer to that depends on who that person is. It's so individual. It also depends on the quality of those calories. Again, a lot of people are knocking themselves out night after night after night with sleeping pills. They may be getting seven to eight hours, but is it sleep? It looks like sleep. It might feel like sleep, but you know what, it's not really sleep. That's part of the question too—the quality of it."

Insufficient Sleep Puts Your Health at Risk

Dr. Naiman is familiar with the studies showing increased health risks when you sleep more or less than a certain amount, but is still cautious about taking these findings as the final word on the matter.

"There is really interesting data," he says. "I think the data is very strong showing that if you don't sleep enough, you're in trouble."

However, it's important to differentiate between occasional lack of sleep, and a chronic pattern. Everyone loses sleep here and there, and your body is typically resilient enough to allow for that. However, when poor sleep becomes a constant, there's no question your health may be at risk.

"The American Cancer Society did a study of a million American adults, and short sleepers showed a dramatic increase in risk of cancers across the board," Dr. Naiman says. "So we know that there is a mountain of data showing if you don't sleep enough, you're going to get yourself sick...

The other end of it, I think, is a little more suspicious. When you say people are sleeping too much, questions arise like 'why?' It may be that in some of those studies they don't have frank illnesses. These are people who don't qualify clinically as having diabetes or heart disease. But they may have metabolic syndrome; they may have very early stage of underlying chronic inflammatory process."

Potential Causes for Sleeping "Too Much"

One of the first indications that you may be getting sick is that your body tries to rest, as sleeping helps strengthen your immune system. So chronically sleeping longer than the average eight or nine hours could be an early indication that you have an underlying illness your body is trying to recover from.

However, the need for more sleep could also be an individual requirement, or even a sign of your body being in tune with a more natural rhythm…

"The data suggests that if you go back 100 years, people were sleeping an average of nine hours a night," Dr. Naiman says. "People also had a very different relationship with sleep at that time. Sleep patterns were very different. It was routine that people woke up in the middle of the night for about an hour or two. It was called night watch. Everybody did it. People also slept during the day.

Think of the Yin and Yang; the white wave representing in this case waking; the dark Yin wave representing night and sleep. There is a dark Yin sphere within the white wave. This is a place of rest in the middle of waking consciousness and natural rhythms. In the middle of the dark Yin wave, there is a place of Yang, a white sphere suggesting that there is a place where awareness, a kind of waking, awareness in the middle of the night.

When we lose sight of that, we overreact to two things. We tend to overreact to being sleepy during the day, and we tend to overreact to being awake at night. And overreactions cause anxiety."

To Nap or Not to Nap…

According to Dr. Naiman, we're actually biologically programmed to nap during the daytime, typically in the middle of the afternoon. Some European countries still adhere to the daily siesta and close shop for a couple of hours in the middle of the day when the heat is also at its most pressing. Most employers in Western countries, however, do not accommodate daily snoozing, so when the natural tendency to get drowsy sets in, you may try to alleviate it with coffee, or simply fight the urge to take a nap.

The problem is, you're now training your body to resist the urge to sleep, which can then lead to being unable to easily fall asleep at night.

"Also, in the middle of the night, when we falsely assume that any kind of awareness is pathological inside, people get up and go, "Oh crap, its insomnia." I've asked hundreds and hundreds of people over the years… "What's the first thing that comes to your mind when you wake up in the middle of the night?" The most common answer I've gotten over the years is, "Oh, shit." People wake up and they curse their wakefulness."

However, as Dr. Naiman explains, occasional waking in the middle of the night, perhaps as many as five times, is actually completely normal. You may pull up the covers or fluff your pillow, then go back to sleep.

"[But] when we learn this automatic judgmental reaction to wakefulness; as soon as there is a spark of it and we judge it, we spin out," he says.

Another common reaction is to look at the clock.

"Patients have actually said to me, "Gosh, I wake up, I get exactly 2:20 every morning." …It's the first thing people—they want to anchor in waking consciousness. They want a sense of control over this ephemeral night consciousness. This addiction to numbers is the problem.

There are nuances with sleep just as there are with waking. There are so many different ways of being awake, different kinds of experiences. Light sleep is fine. Being half awake and half asleep is fine. In fact, I really believe that in any moment in time during the day and at night, it's a mixed percentage. Right now, you and I are talking; we're probably 98 percent awake. I'm just making up a number. There is a restful part of us. We might say we're 2 percent asleep. Closer to bed time it might be 50/50.

What we call being sleepy is being 'part of awake, part asleep.' In the middle of the night when we get up to use the bathroom, we might be 95 percent asleep still and 5 percent awake just to find our way there. We need to allow a mix of these different forms of consciousness."

Guidelines on Optimal Amount of Sleep

Dr. Naiman's recommendation is to simply sleep "enough hours so that your energy is sustained through the day without artificial stimulation, with the exception of a daytime nap." I agree with this functional description rather than trying to come up with a specific numeric range. I would add to that guideline, however, the suggestion to watch out for physical or biological symptoms.

For example, when I push myself and don't get high quality sleep or enough sleep, I'm predisposed to postprandial hypoglycemia. In other words, I have low insulin resistance so when I sleep poorly, it doesn't take much sugar or carbs for it to be easily metabolized and drop my blood sugar—which also makes me really sleepy.

When I get enough sleep, I'm far less susceptible to it.

Dr. Naiman also discusses this, stating that there's solid data showing the connection between insulin resistance and sleep. When participants slept three or four hours less than normal for just a couple of days in a row, they saw a dramatic spike in insulin resistance.

Can You Catch Up on Lost Sleep?

This is another area fraught with confusion. Can you make up for lost sleep by sleeping longer on certain days? According to Dr. Naiman:

"First of all, you can't really bag sleep any more than you can bag oxygen. We just need to replenish it. If you're well slept, you'll be more resilient… If you've under slept and you throw in jetlag on top of that, it gets a lot worse.

In terms of making up for sleep, it is a very common pattern in our world that people short sleep during the week and then sleep in [on the weekend]. It's considered delicious. For me, it's kind of funny. It's like starving yourself during the week and then pigging out on the weekend. It's not the best way to eat, as we know.

You can make up for some lost sleep on the weekend but here is the price: it throws off your circadian rhythm.

Again, the infrastructure of our sleep is this rhythmic drumbeat of day and night, of light and darkness, of sun and melatonin and so on. What most people do on the weekend is actually go to bed later and sleep in much later. You really confuse the poor brain. It's almost like shifting it to another season. It's almost like a little bit of stationary jetlag. You're yanking your circadian rhythm around. It's not something that's recommended."

Which brings up the issue of shift work. How does working nights, or worse, alternating between night- and day-shifts affect your health and well-being?

How Shift Work Affects Your Health

The data is quite clear on this point: Engaging in shift work dramatically increases mortality. According to Dr. Naiman, shift work can decrease your lifespan by about seven years on average! Gastrointestinal disorders are also more common among shift workers.

"The yanking back and forth of the circadian rhythm confuses the body about when to eat, when to digest. Those are some of the early signs," Dr. Naiman warns. "We see dramatic increases in depression among shift workers and then we see a slew of other diseases that are associated with compromised immunity. So if you can, avoid it all.

There are things you can do if you need to do shift work. One is stay on the same shift for a stretch of time. It's much harder to yank back and forth. You can create a prosthetic environment. You're basically turning day and night upside down."

According to Dr. Naiman, preliminary data shows that if you increase your melatonin levels during your night shift—effectively turning it into an artificial day—you can minimize some of the detrimental effects of working during the night. You can find melatonin supplements, either in pill or spray form, in virtually every health food store.

"So you make your night into day and your day into night. When you're driving home from work, you put on a pair of sunglasses. You don't want that light telling you it's time to get up. You cover your windows with aluminum foil and you create an artificial night. You disconnect the phone. You do anything and everything to recreate night so that you can sleep. You use melatonin again at that time. You try not to shift back and forth."

Sleep Timing—Does it Matter?

A common natural health understanding is that every hour of sleep before midnight is equal to two hours after midnight. But is that true? According to Dr. Naiman, this notion is likely more metaphoric than factual.

"[R]oughly the first third to first half of sleep is when we get most of our true deep sleep," he says. "… We spend most of the first part of the night truly sleeping, most of the latter part of the night dreaming… In Chinese medicine, they say the best time to get to sleep is roughly 9:00 or 9:30 pm… roughly a couple of hours after sunset, when there have been enough melatonin raised in our brains that will naturally put us out… [But] I've never seen really hard scientific data. I've seen a lot of anecdotal experience. And there is data that suggests that there is a window of heightened opportunity for falling asleep, which can vary depending on your personal circadian rhythm."

The most important aspect of sleep timing appears to be the consistency of going to bed at the same time every night.

More Information

Dr. Naiman covers a lot of ground in this interview, so to learn more, please listen to the interview in its entirety, or read through the transcript. He also has a great website, www.DrNaiman.com, where you can read more about all things sleep related. You can also find information about his lectures, which is a wonderful way to learn more about the mystery of sleep, and the most effective solutions.

References:

i Mindful Sleep, Mindful Dreams. Dr. Rubin Naiman's website.
Source: Special Interview with Dr. Rubin Naiman, Part 2 of 2.
Related Links:
One of the Most Common Causes of Insomnia
Want a Good Night's Sleep? Then Never Do These Things Before Bed
Americans Don't Get Enough Sleep

Monday, April 2, 2012

Top 10 reasons to avoid your MD

By Dr. Mercola

I've long said that the best strategy for achieving health is avoiding a visit to your doctor in the first place.

Why? Because in many cases you will simply leave the office with a prescription or two, which will rarely solve your health problem.

Most doctor visits result in “solutions” that only suppress your symptoms, often causing other side effects and problems.

Rather than advise patients about the true underlying conditions and real solutions that lead to health, they are left putting toxic Band-Aids on gaping wounds.

As shown in the slideshow above, and as I detail in depth below, there are actually many reasons why avoiding your doctor may be in the best interest of your health …

1. Annual Pap Smears

Many physicians still advise women to receive yearly pap smears, but the newest guidelines from the U.S. Preventive Services Task Force specifically recommend against this. The new recommendations call for women to undergo PAP screening only once every three years, beginning at age 21 and ending around age 65.

When testing is more frequent, or started before age 21, there’s a chance of detecting human papillomavirus (HPV), and associatedlesions, more frequently. If a physician detects such lesions, they will assume they are “pre-cancerous” and treat them accordingly. However, most HPV infections and associated low grade squamous intra-epithelial lesions clear up on their own without treatment,i while the treatment itself can lead to cervical incompetence and/or miscarriage in the future. Since most cases of HPV clear up on their own, this is a case where the treatment may do more harm than good.

That said, PAP smears (which screen for cervical cancer typically associated with HPV) are one of the best tools for preventing cervical cancer deaths – but getting one every year is likely unnecessary.

Evidence shows that screening women for cervical cancer more frequently than every three years does not detect more cancer. Women who have not been exposed to HPV are not at risk for cervical cancer. Further, even if you are exposed and the infection does not clear up on its own (which is not common), it can take 10 years before it progresses to cancer. Cervical cancers are very slow growing, which is why less frequent PAP screens are still effective.

Despite the new PAP screen guidelines, most physicians continue to recommend annual PAP screening to their patients, mostly because they (and their patients) are in the habit of doing so. Some physicians also fear their patients will not come in for annual exams and other screening if the PAP is not required every year.

There is also a good deal of evidence that the revised PAP guidelines are part of a plan to rescue Gardasil (HPV) vaccine sales, which are embarrassingly low. The HPV vaccine is a heavily promoted and very expensive vaccine alternative to PAP smears, but is has been a flop, with less than 27 percent of women opting to receive it, and reports of serious adverse effects continuing to pour in.

2. Mammograms

Only about 1 in 8 women whose breast cancer was identified during a routine mammogram actually had their lives “saved” by the screening, a recent analysis estimatedii – and this does not accurately account for how many women will fall victim to mammogram-induced breast cancer.

Using breast cancer data from The National Cancer Institute and The Centers for Disease Control and Prevention, researchers calculated a 50-year-old woman's likelihood of developing breast cancer in the next 10 years, the odds the cancer would be detected by mammography, and her risk of dying from the cancer over 20 years.

They found that a mammogram has, at best, only a 13 percent probability of saving her life, and that the probability may actually be as low as 3 percent. No matter what analyses they used, including considering women of different ages, the probability of a mammogram saving a life remained below 25 percent. Researchers concluded:

"Most women with screen-detected breast cancer have not had their life saved by screening. They are instead either diagnosed early (with no effect on their mortality) or overdiagnosed."

This bears repeating:

Mammograms often diagnose lesions or tumors that may never threaten a woman's life. They also often result in false positives that lead to over-treatment, i.e. misdiagnosed women often undergo unnecessary mastectomies, lumpectomies, radiation treatments and chemotherapy, which can have a devastating effect on both the quality and length of their lives. Plus, a mammogram uses ionizing radiation, which in and of itself can either induce or contribute to the development of breast cancer.

3. Cold and Flu

Think it’s wise to go to a conventional physician for these? Think again. Thanks to routine over-prescription of antibiotics, and the prescription of inappropriate antibiotics, you’re likely to walk away after being told to take a drug you don’t actually need.

Antibiotics do NOT work against viruses, hence they are useless against colds and flu's. Unfortunately antibiotics are vastly over-prescribed for this purpose. If you have a cold or flu, remember that unless you have a serious secondary bacterial pneumonia, an antibiotic will likely do far more harm than good, because whenever you use an antibiotic, you're increasing your susceptibility to developing infections with resistance to that antibiotic -- and you can become the carrier of this resistant bug, and can spread it to others.

The first thing you want to do when you feel yourself coming down with a cold or flu is to avoid ALL sugars, artificial sweeteners, and processed foods. Sugar is particularly damaging to your immune system -- which needs to be ramped up, not suppressed, in order to combat an emerging infection. This includes fructose from fruit juice, and all types of grains (as they break down into sugar (glucose) in your body).

Ideally, you must address nutrition, sleep, exercise and stress issues the moment you first feel yourself getting a bug. Getting plenty of high quality sleep will be crucial to your recovery. This is when immune-enhancing strategies will be most effective. In addition, the research is quite clear that the higher your vitamin D level, the lower your risk of contracting colds, flu, and other respiratory tract infections. I strongly believe you could avoid colds and influenza entirely by maintaining your vitamin D level in the optimal range.

4. Cholesterol

Many doctors are unaware that a high-fat diet are NOT the cause of heart disease. They are fooled into believing that total cholesterol is an accurate predictor of heart disease. If you visit your physician and you have high cholesterol, you’re likely to be told two things:

Take a statin cholesterol-lowering drug and
Don’t eat saturated fat.
While statin drugs do lower cholesterol very effectively, cholesterol is not the culprit in heart disease. Plus a report by the Massachusetts Institute of Technology claims that no study has ever proven that statins improve all-cause mortalityiii -- in other words, they don't prolong your life any longer than if you'd not taken them at all. And rather than improving your life, they actually contribute to a deterioration in the quality of your life, destroying muscles and endangering liver, kidney and even heart function. The best ways to optimize your cholesterol levels and your heart health have to do with lifestyle measures, including eating healthy minimally processed fats and avoid highly processed vegetable fats and oils that are loaded with toxic omega-6 fats.

5. Depression

Once again, you’re more likely to leave the doctor’s office with a prescription for a drug that could be more dangerous than the problem itself. Every year, 230 million prescriptions for antidepressants are filled, making them one of the most prescribed drugs in the United States. The psychiatric industry itself is a $330 billion industry—not bad for an enterprise that offers little in the way of cures.

Despite all of these prescriptions, more than one in 20 Americans are depressed.iv Of those depressed Americans, 80 percent say they have some level of functional impairment, and 27 percent say their condition makes it extremely difficult to do everyday tasks like work, activities of daily living, and getting along with others.

The use of antidepressant drugs—medicine's answer for depression—doubled in just one decade, from 13.3 million in 1996 to 27 million in 2005.

If these drugs are so extensively prescribed, then why are so many people feeling so low?

Because they don't work at addressing the cause.

Research has confirmed that antidepressant drugs are no more effective than sugar pills. Some studies have even found that sugar pills may produce BETTER results than antidepressants! Personally, I believe the reason for this astounding finding is that both pills work via the placebo effect, but the sugar pills produce far fewer adverse effects.

Many people forget that antidepressants come with a slew of side effects, some of which are deadly. Approximately 750,000 people attempt suicide each year in the US, and about 30,000 of those succeed. Taking a drug that is unlikely to relieve your symptoms and may actually increase your risk of killing yourself certainly does not seem like a good choice. In addition, since most of the treatment focus is on drugs, many safe and natural treatment options that DO work -- like exercise, the Emotional Freedom Technique (EFT), vitamin D, and proper nutrition -- are completely ignored.

6. High Blood Pressure

The definition of what constitutes high blood pressure expanded greatly in 2003, so that drug companies could sell drugs loaded with side effects to 45 million extra people. Because the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (rife with drug industry conflicts of interest) decided that what were in actuality relatively low blood pressure readings were a risk for heart disease, millions more over the years, were suddenly labeled abnormal, and in need of "treatment" for a condition that didn't exist in medical literature until that panel met.

Uncontrolled high blood pressure is a very serious health concern that can lead to heart disease and increases your risk of having a stroke. The good news though is that following a healthy nutrition plan, along with exercising and implementing effective stress reduction techniques will normalize blood pressure in most people.

7. PSA Tests for Prostate Cancer

These tests actually reveal very little, and an irrelevant positive result will likely lead to a biopsy that comes with infection risk. The prostate-specific antigen test (PSA test), analyzes your blood for prostate-specific antigen (PSA), a substance produced by your prostate gland. When higher-than-normal levels of PSA are detected, it is believed that cancer is present. However, PSA screening barely has any impact on mortality rates from prostate cancer. As a result, the U.S. Preventive Services Task Force will soon recommend that men not get screened for prostate cancer.

Today, many experts agree that PSA testing is unreliable at best and useless at worst for accurately diagnosing prostate cancer. Many also agree that routine PSA blood tests often lead to over-diagnosis of prostate cancer, resulting in unnecessary treatments. Similar to mammograms, the PSA screen has become little more than an up-sell technique. The false positive rate is high, and the bulk of the harm is a result of subsequent unnecessary treatments.

Diet is actually a factor that can greatly impact your prostate health and help prevent enlarged prostate and prostate cancer, but many physicians fail to address this.

You'll want to eat as much organic (preferably raw) food as possible, and liberally include fresh herbs and spices, such as ginger. Make sure to limit carbohydrates like sugar/fructose and grains as much as possible to maintain optimal insulin levels, which will help reduce your cancer risk in general. Highly processed or charcoaled meats, pasteurized dairy products, and synthetic trans fats correlate with an increased risk for prostate cancer and should also be avoided.

8. Inappropriate and Unwise Dietary Advice

Most doctors are clueless about what constitutes a healthy diet. As such, they will recommend health catastrophes like artificial sweeteners, vegetable oils in lieu of butter, and fat-free pasteurized dairy products. Most will also neglect to tell you about the foods you could be eating more of to optimize your health, like fermented vegetables, raw dairy products, healthy fats (like saturated and animal-based omega-3s), grass-fed beef and more.

In addition, most are ignorant about the importance of how to cook your food – most foods are best consumed when raw or only lightly cooked, and this includes animal proteins like eggs and meat. A discussion about food quality is essential to health (i.e. getting your meat from a small local farmer instead of a confined animal feeding operation (CAFO)) but you will almost never hear this from your family physician. Wondering how to truly eat healthy? See my nutrition plan for a comprehensive (and free) guide.

9. Prescription Drugs Might Kill You and They Don’t Address the Cause of the Problem

A drug prescription is usually a Band-Aid that gets nowhere near the causes of ill health. And many drugs are dangerous. Last year an analysis of data from the U.S. Centers for Disease Control and Prevention (CDC) revealed that deaths from properly prescribed drugs now outnumber traffic fatalities in the United States! And when you add in deaths attributable to other medical care modalities, like hospital admissions and surgery, the modern medical system becomes the leading cause of death and injury in the United States.

Authored in two parts by Gary Null, PhD, Carolyn Dean, MD ND, Martin Feldman, MD, Debora Rasio, MD, and Dorothy Smith, PhD, the comprehensive Death by Medicine article described in excruciating detail how everything from medical errors to adverse drug reactions to unnecessary procedures caused more harm than good. That was in 2003. In 2010, an analysis in the New England Journal of Medicine found that, despite efforts to improve patient safety in the past few years, the health care system hasn't changed much at all.v

For one of many examples, the birth control pills Yaz and Yasmin, which have been endorsed by a U.S. Food and Drug Administration (FDA) advisory committee, contain a drug called drospirenone that makes women who take it nearly seven times more likely to develop thromboembolism. This is an obstruction of a blood vessel that can lead to deep vein thrombosis, pulmonary embolism, stroke, heart attack and death.

Why did the FDA approve this dangerous drug? It turns out that at least four members of the advisory committee have either done work for the drugs’ manufacturers or licensees, or received research funding from them. According to the Alliance for Natural Health:

“Each of those four panelists who received money from the pill’s manufacturer voted in favor of the pill. Interestingly, the committee’s ruling that the drug’s benefit outweighs the risks was decided by a four-vote margin. Ironically, while the FDA allowed voting by advisors with business connections to drospirenone, the agency barred ... Sidney M. Wolfe, on the grounds that he ... had advised his readers not to take Yaz based on several years of data.”

10. Your Doctor Might Not Even Tell You the Truth

A U.S. telephone survey found that 79 percent of Americans trust their doctor.vi But a recent survey of 1,900 physicians revealed that some are not always open or honest with their patients The results were less than impressive, to put it mildly:

One-third of physicians did not completely agree with disclosing serious medical errors to patients
One-fifth did not completely agree that physicians should never tell a patient something untrue
Amazingly 40% believed that they should hide their financial relationships with drug and device companies to patients
Ten percent said they had told patients something untrue in the previous year
When making health care decisions, you should certainly get your physicians' advice -- that's what you're paying them for, after all. Hopefully you have chosen a health care provider who has similar philosophies about health as you do, and whose expertise you can trust. But remember that when making health care decisions, you must be your own advocate; it’s important to ask questions before opting for tests, procedures or treatments, and it’s your decision if you’d rather opt for less medical intervention while choosing a more natural way of healing your body.

Ultimately, the more you take responsibility for your own health -- in the form of nurturing your body to prevent disease -- the less you need to rely on the "disease care" that passes for health care in the United States. If you carefully follow some basic health principles -- simple things like exercising, eating whole foods, sleeping enough, getting sun exposure, reducing stress in your life, and nurturing personal relationships -- you will drastically reduce your need for conventional medical care, which in and of itself will reduce your chances of suffering ill side effects.

But in the event you do need medical care, seek a health care practitioner who will help you move toward complete wellness by helping you discover and understand the hidden causes of your health challenges ... and create a customized and comprehensive -- i.e. holistic -- treatment plan for you.

References:

i Lancet. 2004 Nov 6-12;364(9446):1678-83. PMID: 15530628
ii Archives of Internal Medicine October 24, 2011
iii How Statins Really Work Explains Why They Don’t Really Work March 11, 2011
iv NCHS Data Brief, No. 7, September 2008
v New England Journal of Medicine November 25, 2010
vi Rasmussen Reports August 24, 2010
Source: CNN March 15, 2012
Source: Alliance for Natural Health March 13, 2012